Transgenic Crops: An Introduction and Resource Guide

APHIS Field Test Permits for Bio-Pharm Crops

Transgenes marked with * are used as selectible markers. These are not the transgenes that make the pharmaceutical product. Name and origin of the transgenes that make the pharmaceutical product are given in the table if the information is available. Often this information is a business secret.

Institution Host plant Transgene Status Test Location Acres

Meristem Therapeutics corn confidential business info issued 06/05/03 CO

Emlay and Associates safflower Growth hormone* - origin: carp. Oleosin* - origin: Arabidopsis thaliana. Phosphinothricin acetyl transferase issued 06/03/03 ND, NV 11

Garst corn
Acetolactate synthase*, confidential business information - origin: human and mouse
pending HI

Chlorogen, Inc. tobacco no information provided issued 05/15/03 SC 1

Dow corn confidential business info issued 06/07/02 AZ, CA

Meristem Therapeutics corn confidential business info - origin: human issued 06/05/02 KY 1

Meristem Therapeutics corn confidential business info issued 05/21/02 VA 5

U of Kentucky tobacco confidential business info; origin: human and mouse issued 05/09/02 KY 0.2

Crop Tech tobacco confidential business info; origin: human issued 05/07/02 SC, VA 0.5

Hawaii Agriculture Research Center sugarcane confidential business info; origin: human issued 01/11/02 HI 0.5

Monsanto corn confidential business info issued 01/11/02 HI 20.8

ProdiGene corn Phosphinothricin acetyl transferase*. Aprotinin - origin: pig. Surface antigen - origin: Hepatitis virus B. Surface antigen - origin: transmissible gastroenteritis virus. gp120 (glycoprotein 120) - origin: simian immunodeficiency virus issued 11/13/01 HI 0.4

Dow corn Phosphinothricin acetyl transferase*. Confidential business information - origin: human issued 10/23/01 HI 7.9

ProdiGene corn Phosphinothricin acetyl transferase*. Enterotoxin subunit B - origin: E. coli issued 10/05/01 FL

Applied Phytologics rice Hygromycin phosphotransferase*. Antitrypsin - origin: human. Dirgent protein - origin: Forsythia intermedia. Laccase - origin: Forsythia intermedia. Lactoferrin - origin: human. Lysozyme - origin: human. Pinoresinol reductase - origin: Forsythia intermedia. Pinoresinol-lariciresinol reductase - origin: Forsythia intermedia. Secoisolariciresinol dehydrogenase - origin: Forsythia intermedia. confidential business info - origin: human HI

ProdiGene corn NptII* issued 07/12/01 HI
1

Iowa State University corn NptII*. Enterotoxin subunit B - origin: E. coli issued 06/14/01 IA 0.2

Crop Tech tobacco confidential business info issued 05/11/01 VA

Crop Tech tobacco confidential business info issued 05/11/01 VA

ProdiGene corn NptII*. confidential business info issued 05/08/01 NE 0.25

ProdiGene corn NptII*. Phosphinothricin acetyl transferase*. Aprotinin - origin: Bos taurus. Enterotoxin subunit B - origin: E. coli. Surface antigen - origin: Hepatitis virus B. Surface antigen - origin: transmissible gastroenteritis virus. gp120 (glycoprotein 120) - origin: simian immunodeficiency virus. confidential business info
issued 05/08/01
NE 53.5

Large Scale Biology tobacco mosaic virus confidential business info issued 04/25/01 KY

Horan Bros. Agri. Enterprises corn NptII*. confidential business info issued 04/25/01
IA
33.2

Prodigene corn NptII*. confidential business info issued 04/19/01 NE 0.7

Applied Phytologics rice NptII*. confidential business info issued 04/19/01 CA 100

ProdiGene corn NptII*. confidential business info issued 04/19/01 NE 0.25

ProdiGene corn NptII*. confidential business info issued 04/17/01 IA, KS, TX 10

Washington State University barley Green fluorescent protein*. Phosphinothricin acetyl transferase*. Amylase - origin: barley. Antithrombin - origin: human. Antitrypsin - origin: human. Lactoferrin - origin: human. Lysozyme - origin: human. Serum albumin - origin: human. issued 03/22/01 WA 3

Monsanto corn C transcriptional activator, confidential business info issued 03/21/01 CA, MO, WA, WI 32

Monsanto corn C transcriptional activator, confidential business info issued 03/21/01 CA, MO, WA, WI 33.4

Monsanto corn confidential business info issued 12/01/00 HI 15

Monsanto corn confidential business info issued 11/03/00 FL, PR 15

Monsanto corn confidential business info issued 11/03/00 FL, PR 15

Monsanto corn confidential business info issued 11/03/00 HI 15

ProdiGene corn Phosphinothricin acetyl transferase*. confidential business info issued 11/03/00 PR

ProdiGene corn no information provided issued 10/13/00 HI 0.1

ProdiGene corn Phosphinothricin acetyl transferase*. confidential business info issued 07/14/00 HI

ProdiGene corn corn Phosphinothricin acetyl transferase. confidential business info issued 05/26/00 NE 2

Applied Phytologics rice Hygromycin phosphotransferase*. NptII*. confidential business info issued 05/15/00 CA 7

Large Scale Biology tobacco mosaic virus confidential business info issued 05/01/00 KY

ProdiGene corn Phosphinothricin acetyl transferase*. confidential business info issued 05/01/00 IA 40

ProdiGene corn confidential business info issued 04/26/00 NE

CropTech tobacco NptII*. Confidential business info - origin: human issued 04/19/00 VA

ProdiGene corn Phosphinothricin acetyl transferase*. Confidential businesses info issued 02/22/00 HI

ProdiGene corn Phosphinothricin acetyl transferase*. confidential business info issued 11/18/99 FL

ProdiGene corn Phosphinothricin acetyl transferase*. confidential business info issued 11/18/99 PR 0.2

Applied Phytologics rice Hygromycin phosphotransferase*. confidential business info issued 10/28/99 HI

Biosource tobacco mosaic virus confidential business info issued 04/30/99 KY 32

Agracetus corn confidential business info issued 04/14/99 IA, IN, WI 24

CropTech tobacco NptII*. confidential business info issued 03/08/99 VA 0.4

ProdiGene corn Phosphinothricin acetyl transferase*. confidential business info issued 03/04/99 IA

Monsanto corn confidential business info issued 02/04/99 HI 1

Monsanto corn confidential business info issued 02/03/99 FL, TX 10

ProdiGene corn Phosphinothricin acetyl transferase*. confidential business info issued 11/25/98 PR

Biosource tobacco etch virus confidential business info issued 07/15/98 KY 0.25

Limagrain corn G glycoprotein issued 06/12/98 IN 0.5

Limagrain corn Phosphinothricin acetyl transferase*. Procollagen - origin : human. issued 06/12/98 IN 0.2

Limagrain corn Phosphinothricin acetyl transferase*. Alpha-hemoglobin - origin: human Beta-hemoglobin - origin: human issued 06/12/98 IL 0.25

Limagrain corn Phosphinothricin acetyl transferase*. Serum albumin - origin: human issued 06/10/98 IA, IL 0.5

Biosource tobacco mosaic virus confidential business info issued 04/24/98 KY 30

Applied Phytologics rice Hygromycin phosphotransferase* - origin: E. coli. Antithrombin - origin: human. Antitrypsin - origin: human. Serum albumin - origin: human. issued 02/25/98 CA

Applied Phytologics rice Hygromycin phosphotransferase*. Confidential business info issued 02/25/98 CA

Prodigene tomato NptII*. issued 01/29/98 TX 1

Biosource tobacco mosaic virus confidential business info issued 11/18/97 FL 1.5

Limagrain corn denied IN

Biosource tobacco mosaic virus confidential business info issued 04/22/97 KY 6

Applied Phytologics rice Hygromycin phosphotransferase*. Aminoglycoside 3'- adenylyltransferase - origin: human. Antithrombin - origin: human. Serum albumin - origin: human. issued 03/31/97 CA

Pioneer rapeseed Phosphinothricin acetyl transferase* - origin: Strep. hygroscopicus. confidential business info issued 09/17/96 CA

Biosource tobacco mosaic virus Phytoene synthase - origin: tomato. Trichosanthin - origin: Trichosanthes kirilowii. issued 06/04/96 KY

RJ Reynolds tobacco mosaic virus confidential business info issued 06/09/95 NC

Noble Foundation alfalfa NptII*. Cholera toxin B - origin: Vibrio cholera. issued 10/10/92 OK

Biosource tobacco mosaic virus Alpha-amylase - origin: rice. Alpha-hemoglobin - origin: rice. Beta-hemoglobin - origin: human. Trichosanthin - origin: Trichosanthes kirilowii. issued 05/01/91 NC

Source: Information Systems for Biotechnology, http://www.nbiap.vt.edu/cfdocs/fieldtests1.cfm. These records were retrieved by searching for the phenotype "Pharmaceutical proteins produced."

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